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Substances Generally Recognized as Safe

Comment period open: closes in 53 days (Dec 9, 2026). Comment on Regulations.gov →

Summary (from the Federal Register abstract)

The Food and Drug Administration (FDA or we) is proposing to require the submission of generally recognized as safe (GRAS) notices for the use of a human or animal food substance purported to be GRAS under the conditions of its intended use under the Federal Food, Drug, and Cosmetic Act (FD&C Act).

Document type
Proposed Rule
Federal Register document number
2026-16296
Published
Aug 11, 2026
Action
Proposed rule.
Docket
FDA-2025-N-3262
Comments posted on Regulations.gov (at last check)
745
RIN
0910-AJ02
CFR parts
21 CFR 170, 21 CFR 570
DATES section (from the document)
Either electronic or written comments on the proposed rule must be submitted by December 9, 2026. Submit comments (including recommendations) on the collection of information under the Paperwork Reduction Act of 1995 by December 9, 2026.
Topics (auto-tagged)
Food & dietary supplements

Source: Federal Register API, document 2026-16296. Federal Register text is a U.S. government work. Confirm dates in the official document; later documents may extend, reopen or correct them.